OverviewGentris provides a full range of services for pharmaceutical and biotech companies and clinical research organizations seeking to deliver safer and more effective drugs.
Bioinformatics
Our bioinformatics team analyzes the gene and/or polymorphism of interest and designs assays to specifically discriminate against homologues, pseudogenes, and other genes.
Our bioinformatics team analyzes the gene and/or polymorphism of interest and designs assays to specifically discriminate against homologues, pseudogenes, and other genes.
Sample Logistics
Gentris has extensive experience in sample logistics. Gentris offers customizable Sample Submission Forms, sample shipping kits, and lab manuals.
Gentris has extensive experience in sample logistics. Gentris offers customizable Sample Submission Forms, sample shipping kits, and lab manuals.
Custom Assay Design and Validation
Our custom assay design and validation process would include meeting with your study team to assess information about what your team is interested in, conducting an initial bioinformatics review, and of course the assay design and validation.
Our custom assay design and validation process would include meeting with your study team to assess information about what your team is interested in, conducting an initial bioinformatics review, and of course the assay design and validation.
Nucleic Acid Isolation
Whether you are interested in immediate testing or storing samples for the future, Gentris has extensive expertise with nucleic acid extraction from multiple sample types.
Whether you are interested in immediate testing or storing samples for the future, Gentris has extensive expertise with nucleic acid extraction from multiple sample types.
Genotyping
Gentris' scientific team helps its clients choose the clinically relevant genes and variants, providing them with customizable, attention-driven service.
Gentris' scientific team helps its clients choose the clinically relevant genes and variants, providing them with customizable, attention-driven service.
UGT1A1 and K-ras Testing
Gentris offers genetic testing for UGT1A1 and K-ras to help identify which patients will benefit from therapy and those who may be harmed from therapy. Genotyping patients in your clinical trial can help reduce adverse drug reactions and save money.
Gentris offers genetic testing for UGT1A1 and K-ras to help identify which patients will benefit from therapy and those who may be harmed from therapy. Genotyping patients in your clinical trial can help reduce adverse drug reactions and save money.
Microarray Services
Microarrays have proven to be a state of the art technique for high throughput comprehensive analysis of thousand of mutations/genes in parallel.
Microarrays have proven to be a state of the art technique for high throughput comprehensive analysis of thousand of mutations/genes in parallel.
Gene Expression Analysis
The scientific team at Gentris has extensive experience in mRNA profiling and qRT-PCR allowing us to design and develop quantitative and specific assays to examine gene induction or repression.
The scientific team at Gentris has extensive experience in mRNA profiling and qRT-PCR allowing us to design and develop quantitative and specific assays to examine gene induction or repression.
Tumor Profiling
Gentris prides itself on identifying targeted tumor specific therapies. Our team has successfully demonstrated how to integrate pharmacogenomics into the development of gene targeted chemotherapy.
Gentris prides itself on identifying targeted tumor specific therapies. Our team has successfully demonstrated how to integrate pharmacogenomics into the development of gene targeted chemotherapy.
Toxicogenomics
Gentris offers toxicogenomic testing for preclinical drug development as well as risk and safey assessment of potential genotoxicants.
Gentris offers toxicogenomic testing for preclinical drug development as well as risk and safey assessment of potential genotoxicants.
Project Management
Each Study Protocol is assigned a dedicated Project Manager/Study Director that has been trained in lab processes as well as demonstrated data interpretation and laboratory proficiencies.
Each Study Protocol is assigned a dedicated Project Manager/Study Director that has been trained in lab processes as well as demonstrated data interpretation and laboratory proficiencies.
Biostorage Facility
Gentris offers storage of DNA, RNA, whole blood, FFPE tissue blocks, plasma, serum, saliva, liver cells, and buccal cells.
Gentris offers storage of DNA, RNA, whole blood, FFPE tissue blocks, plasma, serum, saliva, liver cells, and buccal cells.
Consulting
Gentris has over 40 years of leadership experience pharmacogenomics, quality assurance, and operations. Gentris has published and has spoken on topics such as: informed consent, clinical trial design, assay development and much more.
Gentris has over 40 years of leadership experience pharmacogenomics, quality assurance, and operations. Gentris has published and has spoken on topics such as: informed consent, clinical trial design, assay development and much more.
