Revolutionizing Medicine through Pharmacogenomics

Phone: (919) 465-0100 | pharmadx@cgix.com

Date: June 5 – 7, 2015
Location: Baltimore, MD

RUTHERFORD, N.J., June 1, 2015 — Cancer Genetics, Inc. (Nasdaq: CGIX; “CGI” or “The Company”), an emerging leader in DNA-based cancer diagnostics, today announced that Panna Sharma, President and Chief Executive Officer, will present at the Jefferies 2015 Global Healthcare Conference. The presentation will take place at the Grand Hyatt New York on Thursday, June 4, 2015 at 11:30 a.m. ET in New York City.

A copy of the presentation will be available on Thursday, June 4, 2015 by visiting  “Presentations” in the Investors section on the Company’s website: www.cancergenetics.com.

About Cancer Genetics

Cancer Genetics Inc. is an emerging leader in DNA-based cancer diagnostics. Our tests target difficult to diagnose   hematological, urogenital and HPV-associated cancers.  They are designed to guide the prognosis and treatment of these cancers with the goal of improving outcomes for patients. We have established strong clinical research collaborations with major cancer centers such as Memorial Sloan Kettering, The Cleveland Clinic, Mayo Clinic and the National Cancer Institute.

We also offer a comprehensive range of non-proprietary oncology-focused tests and laboratory services that provide critical genomic information to healthcare professionals and biopharmaceutical companies. Our state-of-the-art reference labs are CLIA certified and CAP accredited in the US and have licensure from several states including New York State.

For more information, please visit or follow us:

Internet: http://www.cancergenetics.com
Twitter: @Cancer_Genetics
Facebook: www.facebook.com/CancerGenetics

Forward Looking Statements: This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. All statements pertaining to future financial and/or operating results, future growth in research, technology, clinical development and potential opportunities for Cancer Genetics, Inc. products and services, along with other statements about the future expectations, beliefs, goals, plans, or prospects expressed by management constitute forward-looking statements. Any statements that are not historical fact (including, but not limited to, statements that contain words such as “will,” “believes,” “plans,” “anticipates,” “expects,” “estimates”) should also be considered to be forward-looking statements. Forward-looking statements involve risks and uncertainties, including, without limitation, risks inherent in the development and/or commercialization of potential products, risks of cancellation of customer contracts or discontinuance of trials, risks that the transaction will not close or, if it closes, will not realize the currently anticipated benefits, uncertainty in the results of clinical trials or regulatory approvals, need and ability to obtain future capital, maintenance of intellectual property rights and other risks discussed in the Company’s Form 10-K for the year ended December 31, 2013 and 10-Q for the quarter ended September 30, 2014 along with other filings with the Securities and Exchange Commission. These forward-looking statements speak only as of the date hereof. Cancer Genetics disclaims any obligation to update these forward-looking statements.

 

Media Relations Contact:
Marie Michellod
Cancer Genetics, Inc.
201-776-1983
Media@cgix.com

Date: May 29 – June 2, 2015
Location: Chicago, IL

Rutherford, N.J., May 29, 2015– Cancer Genetics, Inc. (Nasdaq: CGIX; “CGI” or “The Company”), an emerging leader in DNA-based cancer diagnostics, announced today the presentation of results from a research collaboration with Memorial Sloan Kettering Cancer Center at the 2015 American Society of Clinical Oncology Annual Meeting, taking place at the McCormick Place Convention Center in Chicago, Illinois on May 29-June 2, 2015. The findings of the study, led Dr. Robert Motzer, MD at Memorial Sloan Kettering Cancer Center and Dr. Jane Houldsworth, PhD at CGI, showcase that novel copy number alterations detected by whole genome comparative genomic hybridization may provide insight into sunitinib resistance in patients with advanced renal cell carcinoma.

Details for the poster presentation are the following:

Session: Genitourinary (Nonprostate) Cancer
Date and Time: Monday, June 1st, 2015 1:15PM to 4:45PM CT
Location: S Hall A
Poster #225: “Novel chromosome copy changes to predict clinical response to sunitinib in patients with advanced renal cell carcinoma”

 

Cancer Genetics will be exhibiting in booth 21141.

About Cancer Genetics
Cancer Genetics Inc. is an emerging leader in DNA-based cancer diagnostics. Our tests target difficult to diagnose hematological, urogenital and HPV-associated cancers. They are designed to guide the prognosis and treatment of these cancers with the goal of improving outcomes for patients. We have established strong clinical research collaborations with major cancer centers such as Memorial Sloan Kettering, The Cleveland Clinic, Mayo Clinic and the National Cancer Institute.

We also offer a comprehensive range of non-proprietary oncology-focused tests and laboratory services that provide critical genomic information to healthcare professionals and biopharmaceutical companies. Our state-of-the-art reference labs are CLIA certified and CAP accredited in the US and have licensure from several states including New York State.

For more information, please visit or follow us:
Internet: http://www.cancergenetics.com
Twitter: @Cancer_Genetics
Facebook: www.facebook.com/CancerGenetics

Forward Looking Statements: This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. All statements pertaining to future financial and/or operating results, future growth in research, technology, clinical development and potential opportunities for Cancer Genetics, Inc. products and services, along with other statements about the future expectations, beliefs, goals, plans, or prospects expressed by management constitute forward-looking statements. Any statements that are not historical fact (including, but not limited to, statements that contain words such as “will,” “believes,” “plans,” “anticipates,” “expects,” “estimates”) should also be considered to be forward-looking statements. Forward-looking statements involve risks and uncertainties, including, without limitation, risks inherent in the development and/or commercialization of potential products, risks of cancellation of customer contracts or discontinuance of trials, risks that the transaction will not close or, if it closes, will not realize the currently anticipated benefits, uncertainty in the results of clinical trials or regulatory approvals, need and ability to obtain future capital, maintenance of intellectual property rights and other risks discussed in the Company’s Form 10-K for the year ended December 31, 2013 and 10-Q for the quarter ended September 30, 2014 along with other filings with the Securities and Exchange Commission. These forward-looking statements speak only as of the date hereof. Cancer Genetics disclaims any obligation to update these forward-looking statements.

Media Relations Contact:
Marie Michellod
Cancer Genetics, Inc.
201-776-1983
Media@cgix.com

RUTHERFORD, N.J. & HYDERABAD, INDIA, May 26, 2015 – Cancer Genetics, Inc. (Nasdaq: CGIX; “CGI” or the “Company”) announced today that it was selected by Japanese regenerative medicine company, ReproCELL, Inc., to provide next-generation sequencing (NGS) based services and molecular information to enhance ReproCELL’s translational medicine initiatives.  Under the terms of the agreement, CGI will perform NGS using its recently launched Focus::Hotspot™ panel. This panel targets clinically actionable and validated mutations found in several of the most common solid tumors including breast, colorectal, and lung cancers. CGI expects to process several thousand samples over the next two years at the Company’s genomic lab in Hyderabad, India to aid ReproCELL in advancing its product development portfolio.

ReproCELL, Inc., (4978: Tokyo Stock Exchange) based in Yokohama, Japan, is a global leader in stem-cell technology based regenerative medicine, with operations in Asia, the United States, and Europe. ReproCELL will be utilizing the genomic information derived from CG India’s Focus::Hotspot™ panel to annotate tumor samples and develop a comprehensive database  of cancer mutational information to accelerate translational efforts. Historically, tumor sample registries do not maintain data linking genomic mutations to tumor subtypes. Adding data to tumor sample registries will provide ReproCELL’s biopharmaceutical clients with the ability to access unique genetic signatures, which they may compare with patient samples, facilitating the design of personalized treatment plans.

“Cancer Genetics NGS Focus::Hotspot™ panel will provide us with the capability and translational information to offer our partners access to the genomic insights that will improve the effectiveness of their development efforts,” said Dr. Chikafumi Yokoyama, CEO at ReproCELL. “Our position in next-generation drug discovery and regenerative medicine can be enhanced by focused translational initiatives that integrate genomic and molecular knowledge with our core technology.”

The NGS Focus::Hotspot™ panel provides a comprehensive genomic assessment of the most common solid-tumor cancer mutations, with increased sensitivity compared to other testing methodologies.  Due to its laboratory infrastructure in multiple countries, Cancer Genetics is uniquely positioned to provide NGS-based genomic services to leading and emerging biopharma partners, such as ReproCELL, around the world.

“Working with ReproCELL is a clear example of how genomic insights and regenerative medicine are coming together to transform drug discovery and healthcare.  This effort represents a major milestone for Cancer Genetics, and our India operation, as we continue to focus on its high-quality growth, and on partnering with companies in the region that can utilize our capabilities to accelerate our understanding of cancer.” said Panna Sharma, CEO of Cancer Genetics.

For more information, please visit or follow us:

Internet: www.cancergenetics.com or www.cancergeneticsindia.com

Twitter: @Cancer_Genetics

Facebook: www.facebook.com/CancerGenetics

Media Contacts:

Cancer Genetics, Inc.

Marie-Agnes Patrone-Michellod, PhD.

Tel: 201.528.9182

Email:  marie.michellod@cgix.com

Reprocell

Daigo Obita

Email: info_jp@reprocell.com

ABOUT REPROCELL

ReproCELL was established as a venture company originating from the University of Tokyo and Kyoto University and has been the pioneer in the iPS cell business, succeeding in the commercialization of the world’s first human iPS cell products in 2009 and with the world’s most advanced stem cell research and technology.


ABOUT CANCER GENETICS

Cancer Genetics Inc. is an emerging leader in DNA-based cancer diagnostics, servicing some of the most prestigious medical institutions in the world. Our tests target cancers that are difficult to diagnose and predict treatment outcomes. These cancers include hematological, urogenital and HPV-associated cancers. We also offer a comprehensive range of non-proprietary oncology-focused tests and laboratory services that provide critical genomic information to healthcare professionals, as well as biopharma and biotech companies. Our state-of-the-art reference labs are focused entirely on maintaining clinical excellence and are both CLIA certified and CAP accredited and have licensure from several states including New York State. We have established strong research collaborations with major cancer centers such as Memorial Sloan-Kettering, The Cleveland Clinic, Mayo Clinic and the National Cancer Institute.INVESTORSWEBSITE

Forward Looking Statements: This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. All statements pertaining to future financial and/or operating results, future growth in research, technology, clinical development and potential opportunities for Cancer Genetics, Inc. products and services, along with other statements about the future expectations, beliefs, goals, plans, or prospects expressed by management constitute forward-looking statements. Any statements that are not historical fact (including, but not limited to, statements that contain words such as “will,” “believes,” “plans,” “anticipates,” “expects,” “estimates”) should also be considered to be forward-looking statements. Forward-looking statements involve risks and uncertainties, including, without limitation, risks inherent in the development and/or commercialization of potential products, risks of cancellation of customer contracts or discontinuance of trials, risks that the transaction will not close or, if it closes, will not realize the currently anticipated benefits, uncertainty in the results of clinical trials or regulatory approvals, need and ability to obtain future capital, maintenance of intellectual property rights and other risks discussed in the Company’s Form 10-K for the year ended December 31, 2013 and 10-Q for the quarter ended September 30, 2014 along with other filings with the Securities and Exchange Commission. These forward-looking statements speak only as of the date hereof. Cancer Genetics disclaims any obligation to update these forward-looking statements.

Date: March 21 – 27, 2015
Location: Boston, MA

Date: March 3-7, 2015
Location: New Orleans, LA

RUTHERFORD, N.J., Feb. 26, 2015 (GLOBE NEWSWIRE) – Cancer Genetics, Inc. (Nasdaq:CGIX), an emerging leader in DNA-based cancer diagnostics, announced today that it will report fourth quarter and fiscal 2014 financial results before the market open on Thursday, March 12, 2015. The company will also hold a live investor conference call and webcast at 8:30am Eastern.

Conference Call & Webcast
Thursday, March 12, 2015 at 8:30 a.m. Eastern Time/5:30 a.m. Pacific Time
Domestic: 877-407-4018
International: 201-689-8471
Conference ID: 13601913
Webcast: http://public.viavid.com/player/index.php?id=113220
Replays – Available through March 26, 2015
Domestic: 877-870-5176
International: 858-384-5517
Conference ID: 13601913

About Cancer Genetics

Cancer Genetics, Inc. is an emerging leader in DNA-based cancer diagnostics, servicing some of the most prestigious medical institutions in the world. Our tests target cancers that are difficult to diagnose and predict treatment outcomes. These cancers include hematological, urogenital and HPV-associated cancers. We also offer a comprehensive range of non-proprietary oncology-focused tests and laboratory services that provide critical genomic information to healthcare professionals, as well as biopharma and biotech companies. Our state-of-the-art reference labs are focused entirely on maintaining clinical excellence and are both CLIA certified and CAP accredited and have licensure from several states including New York State. We have established strong research collaborations with major cancer centers such as Memorial Sloan-Kettering, The Cleveland Clinic, Mayo Clinic and the National Cancer Institute.

For more information, please visit or follow us:

Internet: http://www.cancergenetics.com

Twitter: @Cancer_Genetics

Facebook: www.facebook.com/CancerGenetics

CONTACT: Investor Relations
         Hans Vitzthum
         LifeSci Advisors, LLC
         212-915-2568

         Media Relations
         Alison Burchett
         201-528-2053
         media@cgix.com

Source: Cancer Genetics, Inc.

> CGI’s genomic signature, developed in a research collaboration with Memorial Sloan-Kettering, predicts metastasis for clear-cell renal cell carcinoma (ccRCC)
> Clear cell renal cell carcinoma is the most common form of kidney cancer with nearly 43,000 new cases in the US each year and 200,000 globally per year

RUTHERFORD, NJ, February 24, 2015 (Globe Newswire) – Cancer Genetics Inc (Nasdaq: CGIX; “CGI” or “the company”), an emerging leader in DNA-based cancer diagnostics, announced today that it has identified genomic signatures that can differentiate those patients with clear cell renal carcinoma (ccRCC) whose disease is likely to relapse or metastasize.  The signatures were identified in a collaborative study with Memorial Sloan-Kettering Cancer Center (MSKCC) which analyzed and genomically assessed specimens from 144 patients with both primary and metastatic lesions. Genomic signatures identified in this study have the potential to allow for better risk stratification and guided treatment selection for patients with metastatic ccRCC. CGI plans on integrating signatures identified in this study into an NGS-based panel for kidney cancer, which the company expects to be CLIA-certified and available for use for both clinical trials and clinical diagnosis and management of patients.

Clear cell renal cell carcinoma (ccRCC) is the most common subtype of kidney cancer, with approximately 43,000 new cases diagnosed in the US each year. Approximately 20-30% of ccRCC patients relapse within three years after nephrectomy. Identifying patients whose disease is likely to relapse or metastasize is essential for planning appropriate treatment strategies and improving outcome. Copy number variations in samples from patients whose disease had metastasized to the lung or bone (the two most common sites for metastasis of ccRCC) were also identified and validated in an independent dataset. For patients with early-stage disease, accurate prediction of metastatic activity will enable the delivery of personalized precision medicine with the goal of improving outcomes.

Results of the study will be presented at the Genitourinary Cancers Symposium of the American Society of Clinical Oncology (GU-ASCO). The poster presentation, titled “Association of genome-wide copy number alterations with metastasis of clear cell renal cell carcinoma” will be delivered by Banumathy Gowrishankar, Ph.D., principal clinical scientist at Cancer Genetics, on February 28 at 7:00am Eastern Time at the Rosen Shingle Creek in Orlando, Florida.

About the Genitourinary Cancers Symposium

The Genitourinary Cancers Symposium is a specialized oncology event designed for the exchange of the latest strategies in prevention, screening, diagnosis, and treatment of prostate, renal, testicular, and urothelial cancers. The symposium is cosponsored by the American Society for Clinical Oncology (ASCO), American Society for Therapeutic and Radiation Oncology (ASTRO) and the Society for Urologic Oncology (SUO).

About Cancer Genetics

Cancer Genetics, Inc. is an emerging leader in DNA-based cancer diagnostics, servicing some of the most prestigious medical institutions in the world. Our tests target cancers that are difficult to diagnose and predict treatment outcomes. These cancers include hematological, urogenital and HPV-associated cancers. We also offer a comprehensive range of non-proprietary oncology-focused tests and laboratory services that provide critical genomic information to healthcare professionals, as well as biopharma and biotech companies. Our state-of-the-art reference labs are focused entirely on maintaining clinical excellence and are both CLIA certified and CAP accredited and have licensure from several states including New York State. We have established strong research collaborations with major cancer centers such as Memorial Sloan-Kettering, The Cleveland Clinic, Mayo Clinic, Columbia University and the National Cancer Institute.

For more information, please visit or follow us:
Internet: http://www.cancergenetics.com
Twitter: @Cancer_Genetics
Facebook: www.facebook.com/CancerGenetics

Forward Looking Statements: This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. All statements pertaining to future financial and/or operating results, future growth in research, technology, clinical development and potential opportunities for Cancer Genetics, Inc. products and services, along with other statements about the future expectations, beliefs, goals, plans, or prospects expressed by management constitute forward-looking statements. Any statements that are not historical fact (including, but not limited to, statements that contain words such as “will,” “believes,” “plans,” “anticipates,” “expects,” “estimates”) should also be considered to be forward-looking statements. Forward-looking statements involve risks and uncertainties, including, without limitation, risks inherent in the development and/or commercialization of potential products, risks of cancellation of customer contracts or discontinuance of trials, risks that the transaction will not close or, if it closes, will not realize the currently anticipated benefits, uncertainty in the results of clinical trials or regulatory approvals, need and ability to obtain future capital, maintenance of intellectual property rights and other risks discussed in the Company’s Form 10-K for the year ended December 31, 2013 and 10-Q for the quarter ended September 30, 2014 along with other filings with the Securities and Exchange Commission. These forward-looking statements speak only as of the date hereof. Cancer Genetics disclaims any obligation to update these forward-looking statements.

Contacts:

Media Relations
Alison Burchett
Cancer Genetics, Inc.
201-528-2053
media@cgix.com

Investor Relations
Hans Vitzthum
LifeSci Advisors, LLC
212-915-2568

  • CGI’s unique next generation sequencing (NGS) panel, Focus::CLLTM, will be used to assess genetic aberrations and mutations that are clinically relevant and validated for CLL, the most common form of leukemia in the Western hemisphere.
  • CLL accounts for one-third of all leukemias and the Focus::CLLTM panel helps in determining patient outcome and treatment selection.

RUTHERFORD, N.J. and RESEARCH TRIANGLE, N.C., Feb. 17, 2015 (GLOBE NEWSWIRE) — Cancer Genetics, Inc.(Nasdaq:CGIX) (“CGI” or “the Company”), an emerging leader in DNA-based cancer diagnostics, announced today that its unique genomic panel for CLL, Focus::CLLTM, has been selected to provide genomic information for CLL patients in a global clinical trial. The trial is expected to assess several hundred patient specimens during 2015. Focus::CLLTM will be used to help guide patient stratification and management during the trial. The NGS-based panel is the only clinically validated, disease-focused genomic panel being offered in a commercial clinical setting for chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL). Focus::CLLTM is approved for clinical use by the Clinical Laboratory Improvement Amendments (CLIA).

The Focus::CLLTM panel assesses genes with clinical relevance for prognosis, disease management, and treatment selection. The targeted NGS panel was designed to offer actionable and immediately relevant information for clinicians. With an analytical sensitivity of 5%, the test is able to detect biomarker mutations and aberrations that are present at very low levels and which may be missed by other, less sensitive methodologies. Improved sensitivity can lead to enhanced diagnostic and prognostic capabilities for this disease and improved patient outcomes. In addition to being available as an individual test, Focus::CLLTMhas been integrated into the company’s CompleteTM offering for CLL/SLL.

“Our highly focused and custom NGS panel for CLL affords excellent depth of detection of variants in genes of high prognostic value in CLL patients,” said Jane Houldsworth, Ph.D., Vice President of Research and Development at CGI. “For the first time, comprehensive, robust mutation analysis down to at least 5% sensitivity of genes such as TP53, NOTCH1, SF3B1, and uniquely ATM and BIRC3 are being offered in a clinically-regulated setting with results made available to clinicians in a streamlined and informative report to assist in the management of CLL patients.”

CGI’s Focus::CLLTM allows for rapid and highly sensitive sequencing of clinically validated genomic aberrations associated with CLL. The global clinical trial builds upon CGI’s focus on hematological malignancies, and its goal of helping to empower the personalized treatment and management of cancer patients.

“CGI is developing a series of focused, clinically actionable NGS panels that will help deliver actionable information to help patients and clinicians both in routine treatment and in clinical trials,” said Panna Sharma, CEO and President of CGI. “We have seen the need by both payers and biopharma companies to have more targeted, clinically actionable information delivered to influence and guide personalization in an era of targeted, pathway specific therapeutics. Our strategy is to continue developing unique, disease-focused NGS panels that can accelerate the adoption of biomarker driven personalization for cancer patients, aid clinicians and cancer centers, and power clinical trials.”

Chronic lymphocytic leukemia accounts for roughly one-third of all newly diagnosed cases of leukemia, with about 15,700 cases diagnosed in the US each year. Due to disease’s clinical heterogeneity, risk stratification and prognostication is especially important for patient selection in CLL trials.

The company also offers its proprietary MatBA® tests for diffuse large B-cell lymphoma (DLBCL), CLL, follicular lymphoma (FL), and mantle cell lymphoma (MCL) as part of its comprehensive testing for blood-borne cancers.

About Cancer Genetics

Cancer Genetics, Inc. is an emerging leader in DNA-based cancer diagnostics, servicing some of the most prestigious medical institutions in the world. Our tests target cancers that are difficult to diagnose and predict treatment outcomes. These cancers include hematological, urogenital and HPV-associated cancers. We also offer a comprehensive range of non-proprietary oncology-focused tests and laboratory services that provide critical genomic information to healthcare professionals, as well as biopharma and biotech companies. Our state-of-the-art reference labs are focused entirely on maintaining clinical excellence and are both CLIA certified and CAP accredited and have licensure from several states including New York State. We have established strong research collaborations with major cancer centers such as Memorial Sloan-Kettering, The Cleveland Clinic, Mayo Clinic, Columbia University and the National Cancer Institute.

For more information, please visit or follow us:
Internet: http://www.cancergenetics.com
Twitter: @Cancer_Genetics
Facebook: www.facebook.com/CancerGenetics

Forward Looking Statements: This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. All statements pertaining to future financial and/or operating results, future growth in research, technology, clinical development and potential opportunities for Cancer Genetics, Inc. products and services, along with other statements about the future expectations, beliefs, goals, plans, or prospects expressed by management constitute forward-looking statements. Any statements that are not historical fact (including, but not limited to, statements that contain words such as “will,” “believes,” “plans,” “anticipates,” “expects,” “estimates”) should also be considered to be forward-looking statements. Forward-looking statements involve risks and uncertainties, including, without limitation, risks inherent in the development and/or commercialization of potential products, risks of cancellation of customer contracts or discontinuance of trials, risks that the transaction will not close or, if it closes, will not realize the currently anticipated benefits, uncertainty in the results of clinical trials or regulatory approvals, need and ability to obtain future capital, maintenance of intellectual property rights and other risks discussed in the Company’s Form 10-K for the year ended December 31, 2013 and 10-Q for the quarter ended September 30, 2014 along with other filings with the Securities and Exchange Commission. These forward-looking statements speak only as of the date hereof. Cancer Genetics disclaims any obligation to update these forward-looking statements.

Contacts:
Media Relations

Alison Burchett
Cancer Genetics, Inc.
201-528-2053
media@cgix.com

Investor Relations
Hans Vitzthum
LifeSci Advisors, LLC
212-915-2568